Frequent question: What causes vacuolar interface dermatitis?

An interface dermatitis with vacuolar alteration, not otherwise specified, may be caused by viral exanthems, phototoxic dermatitis, acute radiation dermatitis, erythema dyschromicum perstans, lupus erythematosus and dermatomyositis.

What is the cause of interface dermatitis?

Causes. ID is believed to be caused by a reaction similar to an autoimmune disease, in which your immune system, essentially, misfires. Research suggests that, with interface dermatitis, T cells from the immune system become auto-aggressive.

What is Lichenoid interface dermatitis?

Abstract. The terms ‘lichenoid’ and ‘interface’ dermatitis are often used interchangeably to describe an inflammatory pattern characterized histologically by damage to the basal keratinocytes in the epidermis. The mechanism of cell damage of such cells is now best understood as apoptosis, or programmed cell death.

How is interface dermatitis treated?

In addition to the lifestyle and home remedies recommendations below, dermatitis treatment might include one or more of the following: Applying to the affected skin corticosteroid creams, gels or ointments. Applying to the affected skin certain creams or ointments that affect your immune system (calcineurin inhibitors)

What does interface dermatitis mean?

Summary. Interface dermatitis refers to diseases in which the primary pathology is related to the dermo-epidermal junction and is reflected by morphological changes involving the basal cells, the dermo-epidermal junction, and the papillary dermis.

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What foods can cause dermatitis?

Food Sensitivities

Peanuts, milk, soy, wheat, fish, and eggs are the most common culprits. Because kids need a well-rounded diet, don’t stop giving them foods you think might cause eczema flares.

Does dermatitis ever go away?

To treat contact dermatitis successfully, you need to identify and avoid the cause of your reaction. If you can avoid the offending substance, the rash usually clears up in two to four weeks. You can try soothing your skin with cool, wet compresses, anti-itch creams and other self-care steps.

What drugs cause lichenoid dermatitis?

Medications commonly reported to trigger a lichenoid drug eruption include:

  • Antihypertensives – ACE inhibitors, beta-blockers, nifedipine, methyldopa.
  • Diuretics – hydrochlorothiazide, frusemide, spironolactone.
  • Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Phenothiazine derivatives.

Is dermatitis a lupus interface?

Introduction. The 2 main connective tissue disease syndromes characterized by a cell-poor vacuolar interface dermatitis are systemic lupus erythematosus17 and dermatomyositis. 19 Dermatologists apply the designation “acute” lupus erythematosus to the macular erythematous lesions of sudden onset in patients with SLE.

What does lichenoid dermatitis look like?

Lichenoid keratosis typically looks like a small rounded or oval area on the surface of the skin. It can range in size from 3 millimeters to a centimeter or more. It may look like a sore or wart-like growth. It may appear to be inflamed or red, or like a scaly, dry patch on the skin.

Is dermatitis caused by stress?

Anxiety and stress are common triggers that cause eczema to flare up, which then creates more anxiety and stress, which then leads to more eczema flare-ups.

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Is Vaseline good for dermatitis?

Petroleum jelly is often used to treat eczema due to its ability to gently hydrate, moisturize, and heal injured skin. The ointment provides a thick protective layer to sensitive skin, which helps relieve itchiness, flakiness, and inflammation.

Can dermatitis be spread?

No type of dermatitis is contagious. It can’t be spread to anyone else.

What triggers id reaction?

While the exact cause of the id reaction is unknown, the following factors are thought to be responsible: (1) abnormal immune recognition of autologous skin antigens, (2) increased stimulation of normal T cells by altered skin constituents, [8,9] (3) lowering of the irritation threshold, (4) dissemination of …

Is lichen Striatus curable?

There is no effective treatment for lichen striatus and in most cases none is necessary. It usually resolves within 6 months but may leave temporary pale or dark marks (hypopigmentation or hyperpigmentation). Emollients may be used to help treat dryness or itching, if present.

What causes an id reaction?

Causes. Causes include infection with dermatophytosis, Mycobacterium, viruses, bacteria and parasites. Eczematous conditions including contact allergic dermatitis and stasis dermatitis as well as stitches and trauma have also been associated with id reactions.